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Chromosomes-Genetic-Disorder :-

 

Chromosome abnormalities can be of two categories: numerical or structural. Karyotype of an individual can be compared with the normal karyotype to test any chromosomal abnormality. When the chromosome's structure is altered, many kinds of abnormalities can occur: - Deletion, Translocation, Inversion etc. Examples of structural chromosomal abnormalities are Wolf-Hirschhorn syndrome, Robertsonian translocation. Numerical chromosomal disorder is called as Aneuploidy. It occurs when an individual is missing either a chromosome from a pair (monosomy) or has more than two chromosomes of a pair (Trisomy, Tetrasomy, etc.).Example of numerical chromosomal disorder is Down’s syndrome.

 

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