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    Aneuploidy and its types

Aneuploidy is a type of chromosomal abnormality in which numbers of chromosomes are abnormal. It is a genetic disorder causes birth defects. Aneuploidy occurs during cell division due to nondisjunction of chromosomes which leads to unequal distribution of chromosomes to the daughter cells. Weak mitotic checkpoint leads to nondisjunction.

There are different types of Aneuploidy:-

a)      Hypoploidy

                                                        i)            Monosomy (2n-1).

                                                      ii)            Nullisomy (2n-2).

b)      Hyperploidy

(i)         Trisomy (2n+1)

(ii)        Tetrasomy (2n +2).

 

 

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